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. 1991 Jul-Aug;37(4):33-7.

[Regional activity of enkephalin- and angiotensin II-forming peptidases in the rat brain and other peripheral tissues with different craving for ethanol]

[Article in Russian]
O A Gomazkov, A D Panfilov, A P Rostovtsev, N V Komissarova, V V Fomin, O O Grigor'iants
  • PMID: 1661050

[Regional activity of enkephalin- and angiotensin II-forming peptidases in the rat brain and other peripheral tissues with different craving for ethanol]

[Article in Russian]
O A Gomazkov et al. Vopr Med Khim. 1991 Jul-Aug.

Abstract

Activities of enkephalin- and angiotensin II-forming enzymes (carboxypeptidase H and angiotensin-converting enzyme, ACE) were changed in different brain regions and peripheral tissues of rats with various alcohol motivation. The carboxypeptidase H activity was elevated in midbrain, striatum, hypophysis and adrenal glands, while the ACE activity was increased in hypophysis and striatum. The ACE activity was decreased two-fold in thalamo-hypothalamic region of ethanol-preferring rats.

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