Rhabdomyolysis after ingestion of "foxy," a hallucinogenic tryptamine derivative

Mayo Clin Proc. 2006 Apr;81(4):550-1. doi: 10.4065/81.4.550.


"Foxy methoxy" (chemical name, 5-methoxy-N,N-diisopropyltryptamine) is a hallucinogenic tryptamine that has been abused with increasing frequency since its appearance in the late 1990s. Like other drugs in this class, foxy frequently produces feelings of euphoria, disinhibition, and auditory as well as visual hallucinations. The drug has been linked to adverse effects, including restlessness, agitation, gastrointestinal distress, and muscle tension. In light of the relatively recent advent of foxy as a drug of abuse and given the inability of commercial toxicologic screening tests to detect the presence of hallucinogenic tryptamines, additional adverse effects seem probable. We report ingestion of foxy by a healthy 23-year-old man that resulted in rhabdomyolysis and transient acute renal failure.

Publication types

  • Case Reports

MeSH terms

  • 5-Methoxytryptamine / analogs & derivatives*
  • 5-Methoxytryptamine / poisoning
  • Adult
  • Diagnosis, Differential
  • Diuretics / therapeutic use
  • Fluid Therapy
  • Hallucinogens / poisoning*
  • Humans
  • Male
  • Rhabdomyolysis / chemically induced*
  • Rhabdomyolysis / diagnosis
  • Rhabdomyolysis / therapy


  • Diuretics
  • Hallucinogens
  • 5-methoxy-N,N-diisopropyltryptamine
  • 5-Methoxytryptamine