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Comparative Study
, 17 (4), 623-8

Angioplasty Balloon Inflation Pressures During Treatment of Hemodialysis Graft-Related Stenoses

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Comparative Study

Angioplasty Balloon Inflation Pressures During Treatment of Hemodialysis Graft-Related Stenoses

Thomas M Vesely et al. J Vasc Interv Radiol.

Abstract

Purpose: This two-part prospective investigation was designed to determine the balloon inflation pressures required to dilate stenoses associated with hemodialysis grafts and evaluate the burst pressures of five different angioplasty balloons.

Materials and methods: Eighty-nine patients with dysfunctional hemodialysis grafts were enrolled and underwent fistulography. The diagnostic studies revealed 104 stenoses, which were treated with balloon angioplasty. The characteristics of these stenoses and the balloon inflation pressures required to dilate the lesions were recorded. In part two of this investigation, the burst pressures of five different angioplasty balloons were evaluated immediately after their use during angioplasty procedures. Twenty-five balloons of each type were inflated until the balloon burst or 30 atm of pressure was achieved. Several different statistical tests were used to analyze the data set.

Results: The mean balloon inflation pressure required to dilate all 104 stenoses was 17.2 atm. Subgroup analysis revealed that the mean balloon inflation pressure required to dilate 75 venous anastomotic stenoses was 17.9 atm and that a mean pressure of 15.6 atm was required to dilate 29 stenoses located within the native outflow veins. The angioplasty balloon burst pressure experiments revealed that the majority of the tested balloons can be inflated to pressures 5-6 atm greater than the manufacturers' rated burst pressures. However, the margin of safety for overinflation was variable among the balloons tested, and angioplasty balloons experience fatigue with repeated inflations.

Conclusion: The majority of stenoses associated with hemodialysis grafts can be successfully dilated with use of available high-pressure angioplasty balloons.

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