Pertussis serostatus among neonates born to Hispanic women

Clin Infect Dis. 2006 May 15;42(10):1439-42. doi: 10.1086/503567. Epub 2006 Apr 12.

Abstract

The reasons for the higher pertussis incidence among Hispanic infants, compared with among infants of other ethnicities, are unknown. The geometric mean concentration of pertussis toxin-specific immunoglobulin G in serum samples from 220 Hispanic neonates was 8.45 EU/mL, as determined by enzyme-linked immunosorbent assay, and it was significantly lower if mothers were adolescents (4.63 EU/mL; P < or =.001). A lack of maternal immunity is one explanation for pertussis susceptibility in very young Hispanic infants.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Hispanic Americans / statistics & numerical data*
  • Humans
  • Incidence
  • Infant, Newborn
  • Maternal Age
  • Patient Selection
  • Pregnancy
  • Tennessee / epidemiology
  • Texas / epidemiology
  • Whooping Cough / epidemiology*