Pertussis serostatus among neonates born to Hispanic women

Clin Infect Dis. 2006 May 15;42(10):1439-42. doi: 10.1086/503567. Epub 2006 Apr 12.


The reasons for the higher pertussis incidence among Hispanic infants, compared with among infants of other ethnicities, are unknown. The geometric mean concentration of pertussis toxin-specific immunoglobulin G in serum samples from 220 Hispanic neonates was 8.45 EU/mL, as determined by enzyme-linked immunosorbent assay, and it was significantly lower if mothers were adolescents (4.63 EU/mL; P < or =.001). A lack of maternal immunity is one explanation for pertussis susceptibility in very young Hispanic infants.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Female
  • Hispanic Americans / statistics & numerical data*
  • Humans
  • Incidence
  • Infant, Newborn
  • Maternal Age
  • Patient Selection
  • Pregnancy
  • Tennessee / epidemiology
  • Texas / epidemiology
  • Whooping Cough / epidemiology*