Incidence of infection for preterm twins cared for in cobedding in the neonatal intensive-care unit

J Obstet Gynecol Neonatal Nurs. Mar-Apr 2006;35(2):193-8. doi: 10.1111/j.1552-6909.2006.00025.x.


Objectives: To describe the incidence of infection in a group of cobedded preterm twin infants and compare it to the incidence of infection in a cohort of preterm twin infants cared for in the same institution prior to the onset of cobedding.

Design: Retrospective descriptive design.

Setting: Tertiary, referral neonatal intensive-care unit in the Midwest.

Participants: Preterm twin infants between 23 and 35 weeks gestational age.

Methods: Data from 1997 to 2001 (cobedding) compared to data from 1992 to 1996 (no cobedding).

Main outcome measure: Infection as evidenced by positive blood, cerebrospinal fluid, or urine culture or radiographic evidence of pneumonia or necrotizing enterocolitis.

Results: Independent samples t test found the cobedded and non-cobedded infants to be homogenous in demographic data. A 2-way analysis of variance demonstrated no significant effects for cobedded infants on number of sepsis evaluations or number of positive blood cultures. There was a statistically significant difference for number of positive blood cultures at discharge reflecting the increased number of positive blood cultures in the non-cobedded infants. Finally, there were no statistically significant differences found between cobedded and non-cobedded for the presence of pneumonia or necrotizing enterocolitis.

Conclusions: Cobedding of preterm twins cared for in the intensive-care nursery was not associated with an increased incidence of infection. Prospective studies are needed on cobedding before a change in practice is implemented.

MeSH terms

  • Adult
  • Analysis of Variance
  • Bedding and Linens
  • Clinical Nursing Research
  • Cross Infection / epidemiology*
  • Diseases in Twins / epidemiology*
  • Female
  • Humans
  • Incidence
  • Incubators, Infant*
  • Infant, Newborn
  • Infant, Premature, Diseases / epidemiology*
  • Infection Control
  • Intensive Care, Neonatal / methods*
  • Male
  • Midwestern United States / epidemiology
  • Neonatal Nursing / methods
  • Nursing Evaluation Research
  • Research Design
  • Retrospective Studies
  • Risk Factors
  • Sepsis / epidemiology