Effect of polo-like kinase 1 gene silence on cell cycle and drug resistance in K562/A02 cell

Chin Med J (Engl). 2006 Apr 5;119(7):605-8.
No abstract available

MeSH terms

  • Apoptosis / drug effects
  • Cell Cycle
  • Cell Cycle Proteins / antagonists & inhibitors
  • Cell Cycle Proteins / genetics
  • Cell Cycle Proteins / physiology*
  • Doxorubicin / metabolism
  • Doxorubicin / pharmacology
  • Drug Resistance, Neoplasm
  • Humans
  • K562 Cells / cytology
  • K562 Cells / drug effects*
  • Protein-Serine-Threonine Kinases / antagonists & inhibitors
  • Protein-Serine-Threonine Kinases / genetics
  • Protein-Serine-Threonine Kinases / physiology*
  • Proto-Oncogene Proteins / antagonists & inhibitors
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins / physiology*
  • RNA Interference
  • RNA, Small Interfering / pharmacology

Substances

  • Cell Cycle Proteins
  • Proto-Oncogene Proteins
  • RNA, Small Interfering
  • Doxorubicin
  • Protein-Serine-Threonine Kinases
  • polo-like kinase 1