Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
, 152 (Pt 5), 1263-74

Phospholipase A in Gram-negative Bacteria and Its Role in Pathogenesis

Affiliations
Review

Phospholipase A in Gram-negative Bacteria and Its Role in Pathogenesis

Taghrid S Istivan et al. Microbiology.

Abstract

Phospholipase A (PLA) is one of the few enzymes present in the outer membrane of Gram-negative bacteria, and is likely to be involved in the membrane disruption processes that occur during host cell invasion. Both secreted and membrane-bound phospholipase A(2) activities have been described in bacteria, fungi and protozoa. Recently there have been increasing reports on the involvement of PLA in bacterial invasion and pathogenesis. This review highlights the latest findings on PLA as a virulence factor in Gram-negative bacteria.

Similar articles

See all similar articles

Cited by 39 articles

See all "Cited by" articles

MeSH terms

LinkOut - more resources

Feedback