Intradialytic complications during hemodialysis

Hemodial Int. 2006 Apr;10(2):162-7. doi: 10.1111/j.1542-4758.2006.00088.x.


With the advent of developments and advances in hemodialysis machine technology, dialysate water purification, and dialyzers, the clinical spectrum of intradialytic complications has changed over the decades. In the pioneering days of hemodialysis, patients could develop allergic reactions to dialyzer membranes, sterilizing and reprocessing agents, coupled with machines that could not accurately control ultrafiltration rates, and chemically and bacterially contaminated dialysate. Whereas today, although cardiovascular problems remain the most common intradialytic complication, these are mainly due to the time restraints of trying to cope with excessive dialytic weight gains and achieve target dry weight on a thrice weekly schedule, coupled with an aging elderly dialysis population with increasing co-morbidity.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Anaphylaxis / etiology*
  • Anaphylaxis / mortality
  • Anaphylaxis / physiopathology
  • Arrhythmias, Cardiac / etiology*
  • Arrhythmias, Cardiac / mortality
  • Arrhythmias, Cardiac / physiopathology
  • Female
  • Humans
  • Hypotension / etiology*
  • Hypotension / mortality
  • Hypotension / physiopathology
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / therapy
  • Male
  • Prognosis
  • Pulmonary Embolism / etiology*
  • Pulmonary Embolism / mortality
  • Pulmonary Embolism / physiopathology
  • Renal Dialysis / adverse effects*
  • Renal Dialysis / methods
  • Risk Assessment
  • Severity of Illness Index
  • Survival Rate