Anti-inflammatory properties of Type I interferons

Antiviral Res. 2006 Sep;71(2-3):108-16. doi: 10.1016/j.antiviral.2006.03.006. Epub 2006 Apr 4.


The notion that Type I interferons (interferon-alpha and -beta) possess anti-inflammatory potential is supported by data from clinical application in multiple sclerosis, by studies on cultured immune-competent cells and by investigation of experimental diseases in whole animals. These observations deserve the attention of virologists for their potential role in the pathogenesis and clinical management of virus infections.

Publication types

  • Review

MeSH terms

  • Animals
  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use*
  • Disease Models, Animal
  • Humans
  • Inflammation / drug therapy*
  • Interferon Type I / pharmacology
  • Interferon Type I / therapeutic use*
  • Mice
  • Multiple Sclerosis / drug therapy*
  • Virus Diseases / drug therapy*


  • Antiviral Agents
  • Interferon Type I