Avellino corneal dystrophy exacerbated after LASIK: scanning electron microscopic findings

Cornea. 2006 Apr;25(3):306-11. doi: 10.1097/01.ico.0000183536.07275.9a.

Abstract

Purpose: To evaluate the ultrastructure of the cornea of Avellino corneal dystrophy (ACD) exacerbated by LASIK.

Methods: Three ACD patients with exacerbation of granular corneal deposits after LASIK underwent surgical removal of the corneal flap. The corneal flap was processed for scanning electron microscopy (SEM).

Results: SEM of all patients showed abnormal granular clusters in the fibrils of the corneal flap.

Conclusion: Laser in situ keratomileusis induces corneal collagen abnormalities and adhesions of granular material in ACD patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Corneal Dystrophies, Hereditary / etiology*
  • Corneal Dystrophies, Hereditary / ultrastructure*
  • Corneal Stroma / ultrastructure*
  • Female
  • Humans
  • Keratomileusis, Laser In Situ / adverse effects*
  • Male
  • Microscopy, Electron, Scanning
  • Middle Aged
  • Surgical Flaps / pathology*