Recycling of proteins between the endoplasmic reticulum and Golgi complex

Curr Opin Cell Biol. 1991 Aug;3(4):585-91. doi: 10.1016/0955-0674(91)90027-v.

Abstract

Several lines of investigation have shown that protein transport from the endoplasmic reticulum to the Golgi is more complex than previously imagined. Dynamic sorting of both membrane and soluble proteins is now believed to occur on the cis side of the Golgi apparatus with some proteins returning to the endoplasmic reticulum while others travel onwards.

Publication types

  • Review

MeSH terms

  • Amino Acid Sequence
  • Animal Population Groups / metabolism
  • Animals
  • Biological Transport / drug effects
  • Brefeldin A
  • Cell Compartmentation
  • Cyclopentanes / pharmacology
  • Endoplasmic Reticulum / metabolism*
  • Endoplasmic Reticulum / ultrastructure
  • Fungal Proteins / genetics
  • Fungal Proteins / metabolism
  • Genes, Fungal
  • Glycosylation
  • Golgi Apparatus / metabolism*
  • Golgi Apparatus / ultrastructure
  • Models, Biological
  • Molecular Sequence Data
  • Protein Processing, Post-Translational
  • Proteins / metabolism*
  • Receptors, Cell Surface / metabolism
  • Receptors, Peptide*
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism

Substances

  • Cyclopentanes
  • Fungal Proteins
  • HDEL receptor
  • KDEL receptor
  • Proteins
  • Receptors, Cell Surface
  • Receptors, Peptide
  • Brefeldin A