Epilepsy syndromes in infancy

Pediatr Neurol. 2006 Apr;34(4):253-63. doi: 10.1016/j.pediatrneurol.2005.08.005.


An increasing number of infantile epilepsy syndromes have been recognized. However, a significant number of infants (children aged 1-24 months) do not fit in any of the currently used subcategories. This article reviews the clinical presentation, electroencephalographic findings, evolution, and management of the following entities: early infantile epileptic encephalopathy, early myoclonic epilepsy, infantile spasms/West syndrome, severe myoclonic epilepsy of infancy, myoclonic-astatic epilepsy, generalized epilepsy with febrile seizures plus, malignant migrating partial seizures of infancy, hemiconvulsions-hemiplegia-epilepsy, benign myoclonic epilepsy, and benign familial/nonfamilial infantile seizures. Issues related to their classification are addressed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Electroencephalography
  • Epilepsy* / complications
  • Epilepsy* / physiopathology
  • Epilepsy* / therapy
  • Humans
  • Infant
  • Syndrome