Hyperandrogenemia: pathophysiology and its role in ovulatory dysfunction in PCOS

Pediatr Endocrinol Rev. 2006 Jan:3 Suppl 1:198-204.


The most common hormonal disorder that infertile women suffer from is hyperandrogenemia, a disorder believed to show its first signs even from puberty. We discuss the impact of hyperandrogenemia on the normal ovary as well as its potential role and contribution to anovulation and infertility. The early diagnosis and management of hyperandrogenemia in women has been proved to be essential for their health and fertility.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Androgens / blood
  • Androgens / metabolism
  • Anovulation / physiopathology*
  • Female
  • Humans
  • Hyperandrogenism / physiopathology*
  • Infertility, Female / physiopathology
  • Ovarian Follicle / physiopathology*
  • Polycystic Ovary Syndrome / physiopathology*


  • Androgens