Establishment and characterization of a bi-phenotypic leukemic cell line, NALM-19, from a patient with acute leukemia

Hum Cell. 1991 Sep;4(3):257-60.

Abstract

Based on the immunophenotypic and genotypic findings, this acute leukemia cell line, designated NALM-19, is unique in that a partial expression of both B-cell and myeloid cell features are present in this single clonal leukemic cell population. It is noteworthy that two "normal" EB virus-transformed B cell lines, B239 and B240, (paired with NALM-19) were established from the same leukemic blood.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adult
  • Antigens, CD / analysis
  • Blotting, Southern
  • Cell Division
  • Cell Transformation, Viral
  • DNA, Neoplasm / analysis
  • Herpesvirus 4, Human
  • Humans
  • Karyotyping
  • Leukemia / genetics*
  • Leukemia / pathology
  • Male
  • Phenotype*
  • Tumor Cells, Cultured

Substances

  • Antigens, CD
  • DNA, Neoplasm