The influence of maternal ketonuria on fetal well-being tests in postterm pregnancy

Arch Iran Med. 2006 Apr;9(2):144-7.

Abstract

Background: Although it is well-known that postterm pregnancies are associated with the risk of perinatal morbidity and mortality, a comprehensive study on its management is lacking. The aim of present study was to determine whether ketonuria is associated with abnormal fetal test results in pregnancies >40 weeks of gestation.

Methods: In this analytical cross sectional study, a total of 360 pregnant women with gestational age of >40 weeks were evaluated in two hospitals during 2003 - 2004. For each woman, urinary ketones, glucose, pH, proteins, and specific gravity were measured by total screen LSG tapes (Rapignost); in addition, biophysical profile test was recorded and the amniotic fluid index was assessed by ultrasonography.

Results: Ketonuria was found in 34 women (9.44%). Statistical analyses showed that maternal ketonuria was associated with oligohydramnios, abnormal fetal tests, and a significant increase in fetal heart rate decelerations.

Conclusion: Patients with clinically-detectable ketonuria have higher risk for abnormal fetal tests in comparison with those without the disease.

MeSH terms

  • Adult
  • Amniotic Fluid
  • Cross-Sectional Studies
  • Dehydration / complications
  • Female
  • Fetal Distress*
  • Gestational Age
  • Heart Rate, Fetal*
  • Humans
  • Infant, Newborn
  • Ketone Bodies / urine*
  • Oligohydramnios / etiology*
  • Pregnancy
  • Pregnancy, Prolonged / urine*
  • Specific Gravity

Substances

  • Ketone Bodies