[Polymorphism of dental formula and segregation of its variants in a pedigree of kerry blue terrier dogs]

Genetika. 2006 Mar;42(3):414-20.
[Article in Russian]


Polymorphism of the dental formula was analyzed in a sophisticated pedigree of Kerry Blue Terrier. A lack of one or more lower premolars was observed in some dogs. Two different patterns of missing teeth were identified. One pattern consisted in agenesis of a second premolar, often in combination with agenesis of neighbor teeth, including the fourth premolar. In the second pattern, agenesis of a fourth premolar was expressed as an isolated abnormality. It was shown previously that the first pattern is inherited as a recessive trait with near complete penetrance. In this work, the control of a major-gene was demonstrated for the second pattern. This abnormality develops in 70-80% of mutant homozygotes and in no more than 20% of heterozygotes and wild-type homozygotes. It was shown that the two dentition abnormalities are controlled by different genes, which were designated LPA2 and LPA4 (Lower Premolar Agenesis).

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Anodontia / genetics*
  • Anodontia / veterinary*
  • Bicuspid / abnormalities*
  • Dog Diseases / genetics*
  • Dogs / abnormalities*
  • Dogs / anatomy & histology
  • Genes
  • Heterozygote
  • Homozygote
  • Mutation
  • Pedigree*