Antiviral activity of Flos verbasci infusion against influenza and Herpes simplex viruses

Arch Immunol Ther Exp (Warsz). 1991;39(1-2):103-8.


The lyophilized infusion from flowers of Verbascum thapsiforme Schrad. (FVI) showed antiviral activity in in vitro studies against Fowl plague virus, several influenza A strains, influenza B strain as well as Herpes simplex virus. Influenza viruses titer decreased by 1-3 log units, while of H. simplex virus by 2.3 log. FVI has shown virucidal activity on H. simplex virus at 300 micrograms/ml, but did not inactivate influenza viruses. Phytochemical investigations of FVI have shown the presence of flavonoids, iridoids, phenolic acids, saponins, amino acids and free sugars.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antiviral Agents / chemistry
  • Antiviral Agents / isolation & purification*
  • Cells, Cultured
  • Influenza A virus / drug effects
  • Orthomyxoviridae / drug effects*
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Plants, Medicinal*
  • Simplexvirus / drug effects*
  • Virus Replication / drug effects


  • Antiviral Agents
  • Plant Extracts