Genetics and biochemistry of seed flavonoids

Annu Rev Plant Biol. 2006;57:405-30. doi: 10.1146/annurev.arplant.57.032905.105252.


Flavonoids are secondary metabolites that accumulate in most plant seeds and are involved in physiological functions such as dormancy or viability. This review presents a current view of the genetic and biochemical control of flavonoid metabolism during seed development. It focuses mainly on proanthocyanidin accumulation in Arabidopsis, with comparisons to other related metabolic and regulatory pathways. These intricate networks and their fine-tuned regulation, once they are determined, should contribute to a better understanding of seed coat development and the control of PA and flavonol metabolism. In addition, flavonoids provide an interesting model to study various biological processes and metabolic and regulatory networks.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Flavonoids / genetics*
  • Flavonoids / metabolism*
  • Gene Expression Regulation, Plant
  • Seeds / metabolism*
  • Subcellular Fractions / metabolism


  • Flavonoids