TopoICE-R: 3D visualization modeling the topology of DNA recombination

Bioinformatics. 2006 Jul 15;22(14):1790-1. doi: 10.1093/bioinformatics/btl164. Epub 2006 May 3.

Abstract

TopoICE-R is a three-dimensional visualization and manipulation software for solving 2-string tangle equations and can be used to model the topology of DNA bound by proteins such as recombinases and topoisomerases.

Availability: This software, manual and example files are available at www.knotplot.com/download for Linux, Windows and Mac.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Binding Sites
  • Computer Graphics
  • Computer Simulation
  • DNA / chemistry*
  • DNA / ultrastructure
  • Imaging, Three-Dimensional / methods
  • Models, Chemical*
  • Models, Molecular*
  • Nucleic Acid Conformation
  • Protein Binding
  • Protein Conformation
  • Recombinases / chemistry*
  • Recombinases / ultrastructure
  • Recombination, Genetic*
  • Software*
  • User-Computer Interface*

Substances

  • Recombinases
  • DNA