Aims: To review the most important clinical trials which have impacted the management of gynaecological cancers, in conjunction with some ongoing studies of interest.
Methods: PubMed and Cochrane databases were searched to find clinical trials and meta-analyses in vulva, cervical, endometrial and ovarian cancers. Other pertinent literature was also used.
Results: The majority of trials related to ovarian and cervical cancers, and the least associated with vulval cancer.
Conclusions: To ensure evidence based medicine, trials in gynaecological cancers must be supported. Notably, surgical trials are on the increase in the last decade, but are still a minority when compared with non-surgical interventions.