Gorham-Stout syndrome in a male adolescent-case report and review of the literature

J Pediatr Hematol Oncol. 2006 Apr;28(4):231-3. doi: 10.1097/01.mph.0000203721.83566.e6.

Abstract

Gorham-Stout syndrome is a rare disease characterized by vascular proliferation in the bones, effecting osteolysis. When it is complicated by chylothorax, the prognosis is poor. The present case illustrates successful management of chylothorax by a combination of surgery (thoracic duct ligation and excision of lymphangiomatous tissue combined with pleurodesis) and treatment with alpha-2b interferon. Treatment in 38 published cases is reviewed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Humans
  • Male
  • Osteolysis, Essential / diagnostic imaging*
  • Osteolysis, Essential / surgery*
  • Radiography