Effect of calcination cycles on the preparation of tin oxide based traditional drug: studies on its formation and characterization

M P Wadekar; C V Rode; Y N Bendale; K R Patil; A B Gaikwad; A A Prabhune

doi:10.1016/j.jpba.2006.03.032

Effect of calcination cycles on the preparation of tin oxide based traditional drug: studies on its formation and characterization

J Pharm Biomed Anal. 2006 Jun 16;41(4):1473-8. doi: 10.1016/j.jpba.2006.03.032. Epub 2006 May 8.

Authors

M P Wadekar¹, C V Rode, Y N Bendale, K R Patil, A B Gaikwad, A A Prabhune

Affiliation

¹ Division of Biochemical Sciences, National Chemical Laboratory, Pune 411008, India.

PMID: 16682160
DOI: 10.1016/j.jpba.2006.03.032

Abstract

The preparation method of metal based Indian traditional drugs involves conversion of a pure metal into its oxide by repeated high temperature calcination cycles. In this work, the effect of number of calcination cycles followed in the preparation of tin oxide based Ayurvedic drug, 'vanga bhasma' was studied by a systematic characterization of the drug samples after various calcination stages. It was found that tin was in the form of Sn4+ state and that the formation of SnO2 proceeded step-wise through Sn(OH)4.

MeSH terms

Chemistry, Pharmaceutical / methods*
Medicine, Ayurvedic*
Oxidation-Reduction
Particle Size
Plant Extracts / chemistry*
Tin Compounds / chemistry*

Substances

Plant Extracts
Tin Compounds
stannic oxide