The impact of lesion length on angiographic restenosis after vertebral artery origin stenting

Eur J Vasc Endovasc Surg. 2006 Oct;32(4):379-85. doi: 10.1016/j.ejvs.2006.02.016. Epub 2006 May 6.


Objective: To evaluate the effect of lesion length on in-stent restenosis (ISR) of vertebral artery (VA) origin stenting.

Methods: We retrospectively analyzed the medical and radiological records of patients receiving VA origin stenting from March 1999 to June 2005. They were subdivided according to lesion length. ISR was defined as >50% diameter narrowing in stent.

Results: Eighty symptomatic patients (64 male, mean age 72 years) with 90 lesions treated with balloon expandable tubular coronary stents were enrolled. There were 34 patients with 38 short lesions (length<or=5 mm, group 1), 37 patients with 42 medium lesions (length>5 mm, <10 mm, group 2) and 9 patients with 10 long lesions (length>or=10 mm, group 3). Eighty seven bare-metal stents and 3 drug-eluting stents were implanted. Repeat angiography was done in 40 lesions (44%) at 11.7+/-9.6 months. The ISR rate in group 1, 2, 3 is 21%, 29%, and 50% (p=0.486). Multivariable Cox regression analysis showed lesion length was the only significant independent predictor of ISR (hazard ratio: 1.19, p=0.039).

Conclusion: ISR of VA origin stenting is common. Lesion length is an important predictor of ISR in VA origin stenting.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon
  • Constriction, Pathologic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Radiography
  • Recurrence
  • Stents*
  • Vertebral Artery* / diagnostic imaging
  • Vertebral Artery* / pathology
  • Vertebrobasilar Insufficiency / diagnostic imaging
  • Vertebrobasilar Insufficiency / pathology
  • Vertebrobasilar Insufficiency / therapy*