Toxicological assessments of Gulf War veterans
- PMID: 16687269
- PMCID: PMC1569627
- DOI: 10.1098/rstb.2006.1825
Toxicological assessments of Gulf War veterans
Abstract
Concerns about unexplained illnesses among veterans of the 1991 Gulf War appeared soon after that conflict ended. Many environmental causes have been suggested, including possible exposure to depleted uranium munitions, vaccines and other drugs used to protect troops, deliberate or accidental exposure to chemical warfare agents and pesticides and smoke from oil-well fires. To help resolve these issues, US and UK governments have sought independent expert scientific advice from prestigious, independent scientific and public health experts, including the US National Academies of Science and the UK Royal Society and Medical Research Council. Their authoritative and independent scientific and medical reviews shed light on a wide range of Gulf War environmental hazards. However, they have added little to our understanding of Gulf War veterans' illnesses, because identified health effects have been previously well characterized, primarily in the occupational health literature. This effort has not identified any new health effects or unique syndromes associated with the evaluated environmental hazards. Nor do their findings provide an explanation for significant amounts of illnesses among veterans of the 1991 Gulf War. Nevertheless, these independent and highly credible scientific reviews have proven to be an effective means for evaluating potential health effects from deployment-related environmental hazards.
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References
-
- Abou-Donia M.B, Wilmarth K.R, Abdel-Rahman A.A, Jensen K.F, Oehme F.W, Kurt T.L. Increased neurotoxicity following concurrent exposure to pyridostigmine bromide, DEET, and chlorpyrifos. Fundam. Appl. Toxicol. 1996a;34:201–222. doi:10.1006/faat.1996.0190 - DOI - PubMed
-
- Abou-Donia M.B, Wilmarth K.R, Jensen K.F, Oehme F.W, Kurt T.L. Neurotoxicity resulting from coexposure to pyridostigmine bromide, DEET, and permethrin: implications of Gulf War chemical exposures. J. Toxicol. Environ. Health. 1996b;48:35–56. doi:10.1080/009841096161456 - DOI - PubMed
-
- Archer V.E, Wagoner J.K, Lundin F.E., Jr Cancer mortality among uranium mill workers. J. Occup. Med. 1973;15:11–14. - PubMed
-
- Armed Forces Epidemiological Board (AFEB) 1996 Report on health effects of low level exposure to chemical agents. Available from URL: http://www.ha.osd.mil/afeb/reports/default.cfm [Accessed 2006 Feb 22].
-
- Armed Forces Epidemiological Board (AFEB) 1999 Vaccines in the military: a department of defense-wide review of vaccine policy and practice. Available from URL: http://www.ha.osd.mil/afeb/reports/default.cfm [Accessed 2006 Feb 22].
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