Clinical profile, diagnosis and management of patients presenting with symptomatic pulmonary embolism

Indian J Chest Dis Allied Sci. 2006 Apr-Jun;48(2):111-4.

Abstract

Objective: To study the clinical profile and diagnostic methods in patients with symptomatic pulmonary embolism (PE).

Methods: Prospective assessment of clinical features, radiology and outcome of patients presenting with symptomatic PE over an 18-month period.

Results: During study period, 24 patients with a mean age of 39 +/- 12.1 years were diagnosed to have symptomatic pulmonary embolism. Dyspnoea (91.7%) and cough (58.3%) were the predominant complaints. Spiral computed tomographic pulmonary angiography (CTPA) was performed in 21 (87.5%) patients and perfusion scans in 14 (58.4%) patients. Echocardiography performed in all patients revealed evidence of pulmonary artery hypertension and right ventricular dyskinesia in 20 (83.3%) and 15 (62.5%) patients, respectively. Thrombolysis with streptokinase was performed in 14 (58.3%) patients. All patients received low molecular weight heparin followed by warfarin. Of the 24 patients, 20 (83.3%) were discharged and are under regular follow-up; four patients died.

Conclusions: Pulmonary embolism is a common problem and can be easily diagnosed provided it is clinically suspected. Early diagnosis and aggressive management is the key to successful outcome.

MeSH terms

  • Adult
  • Female
  • Humans
  • India
  • Male
  • Middle Aged
  • Prospective Studies
  • Pulmonary Embolism* / complications
  • Pulmonary Embolism* / diagnosis
  • Pulmonary Embolism* / therapy