3D power Doppler analysis of the vascularisation in tumours of the oral cavity

Ultraschall Med. 2007 Feb;28(1):40-4. doi: 10.1055/s-2006-926716. Epub 2006 May 15.

Abstract

Purpose: The aim of this study was to determine the volume and vascularisation of tumours by three-dimensional (3D) power Doppler ultrasound in patients with "tumours of the oral cavity".

Materials and methods: Three-dimensional (3D) power Doppler ultrasound investigation was performed pre-operatively on 49 patients with carcinomas of the oral cavity. Digitally-stored data were analysed with 3D View program software, a part of which is the "VOCAL-Imaging program". By using VOCAL, the borders of a structure (tumour) can be determined and its volume calculated. The vascularisation of the tumour was determined by analysing three-dimensional colour histograms, and the vascularisation indices were calculated.

Results: Vascularisation indices VI and VFI were significantly higher in patients with neck metastases. The differences between the vascularisation indices in N+ and N0 necks were statistically significant (p < 0.05). The flow index (FI) values between N+ and N0 necks were not statistically different.

Conclusion: The volume and vascularisation of tumours of the oral cavity could be determined effectively by three-dimensional power Doppler ultrasound. Tumour vascularisation is higher in metastatic than in non-metastatic tumours.

MeSH terms

  • Carcinoma, Squamous Cell / diagnostic imaging*
  • Carcinoma, Squamous Cell / pathology
  • Humans
  • Image Processing, Computer-Assisted
  • Imaging, Three-Dimensional
  • Mouth / diagnostic imaging*
  • Mouth Neoplasms / diagnostic imaging*
  • Mouth Neoplasms / pathology
  • Ultrasonography