Twenty Years of Clinical Islet Transplantation at the Diabetes Research Institute--University of Miami

Clin Transpl. 2004;177-204.


Transplantation of allogeneic pancreatic islets for the treatment of patients with Type 1 diabetes mellitus (T1DM) is now a reality. The steady progress that has allowed for the recent successful clinical trials world-wide follows a steep learning curve and the perseverance of the international islet transplantation community. The Clinical Islet Transplant Program at the Diabetes Research Institute - University of Miami has contributed to the progress in the field with a 20-year track record. It has been a long journey and despite the intermediate success, more work is needed in order to achieve the ultimate goal of a safe and long-lasting treatment for patients with T1DM.

Publication types

  • Historical Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Academies and Institutes
  • Bone Marrow Cells / cytology
  • Cell Separation / methods
  • Clinical Protocols
  • Clinical Trials as Topic
  • Diabetes Mellitus / surgery
  • Florida
  • Graft Survival
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Immunosuppression / methods
  • Islets of Langerhans Transplantation / history
  • Islets of Langerhans Transplantation / methods
  • Islets of Langerhans Transplantation / trends*
  • Patient Selection
  • Tissue Donors
  • Tissue and Organ Procurement / methods