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. 2006 Aug;13(8):1256-9.
doi: 10.1038/sj.cdd.4401962. Epub 2006 May 19.

The p53-Bcl-2 Connection

Free PMC article

The p53-Bcl-2 Connection

M T Hemann et al. Cell Death Differ. .
Free PMC article


Figure 1
Figure 1
Overcoming the antiapoptotic threshold set by Bcl-2 family members. p53-dependent signals, including the induction of Bax, Puma and Noxa and direct inhibition of Bcl-2, synergize with p53-independent signals, like the induction of Bim, to antagonize Bcl-2 function and promote apoptosis

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