Hypoglycemic effect of Bauhinia cheilandra in rats

E R Almeida; M C Guedes; J F C Albuquerque; H Xavier

doi:10.1016/j.fitote.2006.03.001

Hypoglycemic effect of Bauhinia cheilandra in rats

Fitoterapia. 2006 Jun;77(4):276-8. doi: 10.1016/j.fitote.2006.03.001. Epub 2006 Apr 18.

Authors

E R Almeida¹, M C Guedes, J F C Albuquerque, H Xavier

Affiliation

¹ Laboratório de Farmacologia do Departamento de Antibiótico, Universidade Federal de Pernambuco CEP 50670-901 Recife, PE, Brazil. ealmeida@ufpe.br

PMID: 16713131
DOI: 10.1016/j.fitote.2006.03.001

Abstract

The extract of the methanolic leaves of Bauhinia cheilandra (BC) was tested on glucose loaded and alloxan-induced diabetic rats. In both tests, the methanolic extract at doses of 300, 600, and 900 mg/kg, has shown a statistically significant and considerable hypoglycemic activity.

MeSH terms

Administration, Oral
Alloxan
Animals
Bauhinia*
Blood Glucose / drug effects*
Diabetes Mellitus, Experimental / blood
Diabetes Mellitus, Experimental / chemically induced
Diabetes Mellitus, Experimental / drug therapy*
Dose-Response Relationship, Drug
Female
Hypoglycemic Agents / administration & dosage
Hypoglycemic Agents / pharmacology*
Hypoglycemic Agents / therapeutic use
Male
Phytotherapy*
Plant Extracts / administration & dosage
Plant Extracts / pharmacology*
Plant Extracts / therapeutic use
Plant Leaves
Rats
Rats, Wistar

Substances

Blood Glucose
Hypoglycemic Agents
Plant Extracts
Alloxan