Conformational change of membrane proteins leads to shape changes of red blood cells

Bioelectrochemistry. 2007 Jan;70(1):122-6. doi: 10.1016/j.bioelechem.2006.03.019. Epub 2006 Apr 5.


High-resolution atomic force microscopy (AFM) allows a new insight into the surface of mammalian cells. Using the human red blood cell (RBC) as a model, we have demonstrated an important correlation between the conformation of membrane proteins measured from the external face of the cell and the cell shape.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Shape*
  • Erythrocytes / cytology*
  • Erythrocytes / ultrastructure*
  • Humans
  • Membrane Proteins / chemistry*
  • Membrane Proteins / ultrastructure*
  • Microscopy, Atomic Force


  • Membrane Proteins