The genetics of Salmonella genomic island 1

Microbes Infect. 2006 Jun;8(7):1915-22. doi: 10.1016/j.micinf.2005.12.028. Epub 2006 Mar 27.


Multidrug-resistant Salmonella enterica serovar Typhimurium phage type DT104, resistant to ampicillin, chloramphenicol/florfenicol, streptomycin, sulfonamides, and tetracycline, has disseminated worldwide. The resistance genes reside on the 43-kb Salmonella genomic island 1 (SGI1), which is transferable. Drug-resistant variants of SGI1 have been identified in numerous serotypes. Strains harboring SGI1 may be more virulent and have a tendency to rapidly disseminate.

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Resistance, Multiple, Bacterial / genetics*
  • Genomic Islands / genetics*
  • Humans
  • Salmonella Infections / epidemiology
  • Salmonella Infections / microbiology
  • Salmonella Infections, Animal / epidemiology
  • Salmonella Infections, Animal / microbiology
  • Salmonella typhimurium / genetics*
  • Salmonella typhimurium / pathogenicity
  • Virulence