Parallel pathways of virus recognition

Benjamin R Tenoever; Tom Maniatis

doi:10.1016/j.immuni.2006.05.006

Parallel pathways of virus recognition

Immunity. 2006 May;24(5):510-2. doi: 10.1016/j.immuni.2006.05.006.

Authors

Benjamin R Tenoever¹, Tom Maniatis

Affiliation

¹ Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

PMID: 16713969
DOI: 10.1016/j.immuni.2006.05.006

Abstract

Viruses trigger signaling pathways of innate immunity. In this issue, it is shown that the mitochondrial antiviral signaling protein is critical for intracellular detection signaling, but is dispensable for the activation of innate immunity via Toll-like receptors.

Publication types

Review
Comment

MeSH terms

Adaptor Proteins, Signal Transducing / immunology*
Animals
Humans
Immunity, Innate*
Membrane Proteins / immunology
Mitochondrial Proteins / immunology*
Nerve Tissue Proteins / immunology
Receptors, Cell Surface
Signal Transduction / immunology*
Viruses / immunology*

Substances

Adaptor Proteins, Signal Transducing
Membrane Proteins
Mitochondrial Proteins
Nerve Tissue Proteins
Receptors, Cell Surface
Robo3 protein, mouse