Imaging features of crystal-induced arthropathy

Rheum Dis Clin North Am. 2006 May;32(2):427-46, viii. doi: 10.1016/j.rdc.2006.04.001.


Crystal-induced arthropathies constitute a spectrum of inflammatory arthritides that is induced by cellular reaction to crystal deposition in and around joints. A variety of microcrystals may be deposited and can induce an inflammatory response. The three most common types of crystal-induced arthropathy are gout, calcium pyrophosphate dihydrate deposition disease, and calcium hydroxyapatite deposition disease. Each has a characteristic clinical presentation, crystal type that may be aspirated from affected tissues, and radiographic appearance. Each of these entities may occur as a primary abnormality or secondary to an underlying disorder. Sometimes these diseases may coexist in the same joint or individual. Imaging frequently plays a crucial role in the diagnosis of crystal-induced arthropathies and may help to monitor disease progression and treatment response.

Publication types

  • Review

MeSH terms

  • Arthrography
  • Chondrocalcinosis / diagnostic imaging*
  • Chondrocalcinosis / metabolism
  • Crystallization
  • Gout / diagnostic imaging*
  • Gout / metabolism
  • Humans
  • Hydroxyapatites / metabolism


  • Hydroxyapatites