Clinical outcomes of 3 fusion methods through the posterior approach in the lumbar spine

Spine (Phila Pa 1976). 2006 May 20;31(12):1351-7; discussion 1358. doi: 10.1097/01.brs.0000218635.14571.55.


Study design: This prospective randomized study compared 3 fusion methods: posterolateral fusion (PLF), posterior lumbar interbody fusion (PLIF), and PLIF combined with PLF (PLF+PLIF).

Objectives: To compare the outcomes of the 3 fusion methods and find a useful fusion method.

Summary of background data: Many studies have shown clinical results, advantages, and postoperative complications of each fusion method, but few have compared the 3 fusion methods prospectively.

Methods: A total of 167 patients who underwent 1 or 2-level fusion surgery because of degenerative lumbar disease from January 1996 to September 2000 were studied. Minimum follow-up was 3 years. The patients were randomized into 1 of 3 treatment groups: group 1 (PLF; n = 62); group 2 (PLIF; n = 57); and group 3 (PLF+PLIF; n = 48). A visual analog scale, the Oswestry Disability Questionnaire, and Kirkaldy-Willis criteria were used to measure low back pain, leg pain, and disability. For radiologic evaluation, disc height, lumbar lordosis, segmental angle, and bone union were examined. Postoperative complications were also analyzed.

Results: At the last follow-up, good or excellent results were obtained in 50 cases of PLF (80.7%), 50 cases of PLIF (87.8%), and 41 cases of PLF+PLIF (85.5%). No statistical differences were found among the 3 groups (P = 0.704). All methods indicated significant improvement in the disc height (P < 0.05), with PLF having the highest loss in disc height. Lumbar lordosis and segmental angle increased significantly, and improvement of the segmental angle in the 3 fusion methods had statistically significant differences. The nonunion rates at the last follow-up in the 3 fusion groups were not statistically significant, with 8% in group 1, 5% in group 2, and 4% in group 3 (P > 0.05). Complications included deep infection in 3 cases, transient nerve palsy in 4, permanent nerve palsy in 1, and donor site pain in 6.

Conclusions: No significant differences in clinical results and union rates were found among the 3 fusion methods. PLIF had better sagittal balance than PLF. PLIF without PLF had advantages of the elimination of donor site pain, shorter operating time, and less blood loss.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Aged
  • Disability Evaluation
  • Female
  • Humans
  • Leg
  • Lordosis / diagnostic imaging
  • Lordosis / etiology
  • Low Back Pain / etiology
  • Low Back Pain / physiopathology
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / surgery*
  • Male
  • Middle Aged
  • Pain / etiology
  • Pain / physiopathology
  • Paralysis / etiology
  • Radiography
  • Spinal Diseases / complications
  • Spinal Diseases / diagnostic imaging
  • Spinal Diseases / surgery*
  • Spinal Fusion / adverse effects
  • Spinal Fusion / methods*
  • Surgical Wound Infection
  • Treatment Outcome