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Review
, 27 (2 Suppl 1), S3-6

The Discovery of Immunoglobulin E

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  • PMID: 16722325
Review

The Discovery of Immunoglobulin E

S G O Johansson. Allergy Asthma Proc.

Abstract

As early as 1919, from a case of transient asthma caused by blood transfusion, the presence in serum of a factor causing allergy was proposed. Despite intense search, this factor was not identified until 1968, when immunoglobulin E (IgE) was officially recognized by the World Health Organization. The knowledge about IgE mediating allergy has greatly improved our understanding of allergic inflammation and diagnoses and treatment of allergic diseases.

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