Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci

Genomics. 1991 Jan;9(1):78-89. doi: 10.1016/0888-7543(91)90223-2.


An interspecific backcross between lab mice and Mus spretus was used to construct a multilocus map of Chromosome 17 consisting of 12 new anonymous loci and 9 anchor loci. In addition, 7 anonymous DNA loci were added to the Chr 17 map for the BXD strains. Although we were able to identify readily the most likely gene order in the interspecific backcross, we found no evidence for an unambiguous gene order using the BXD recombinant inbred strains. Comparison of the interspecific backcross map and the BXD RI strain map revealed evidence in the interspecific backcross for a longer total genetic length, enhanced recombination distal to H-2, a segment showing suppressed recombination, and strong interference.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Chromosome Mapping*
  • Crosses, Genetic
  • DNA / genetics
  • Genetic Markers*
  • Mice
  • Mice, Inbred C57BL
  • Muridae
  • Polymorphism, Restriction Fragment Length
  • Recombination, Genetic


  • Genetic Markers
  • DNA