Hyperperfusion syndrome after clipping of an unruptured aneurysm. Case report

Neurol Med Chir (Tokyo). 2006 May;46(5):248-50. doi: 10.2176/nmc.46.248.


A 41-year-old man developed hyperperfusion 24 hours after undergoing successful clipping surgery for an unruptured middle cerebral artery aneurysm with temporary occlusion for 7 minutes. The patient exhibited motor aphasia 24 hours after surgery. Single photon emission computed tomography revealed hyperperfusion. The patient was sedated for 72 hours using propofol, and his symptoms gradually resolved. He returned to his previous job 2 months after surgery. Hyperperfusion syndrome is possible following any aneurysm surgery, including surgery for unruptured aneurysms using the temporary occlusion technique.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / blood supply*
  • Brain / pathology
  • Cerebrovascular Circulation / physiology
  • Hemodynamics / physiology
  • Humans
  • Intracranial Aneurysm / pathology
  • Intracranial Aneurysm / surgery*
  • Magnetic Resonance Imaging
  • Male
  • Neurosurgical Procedures / methods*
  • Postoperative Complications*
  • Syndrome
  • Tomography, Emission-Computed, Single-Photon