Hydrocortisone: an important cutaneous allergen

Lancet. 1991 Mar 30;337(8744):761-2. doi: 10.1016/0140-6736(91)91373-3.


We have found a high incidence (4.8%) of allergy to hydrocortisone in patients with suspected allergic contact dermatitis. In view of this finding we would suggest that, in any condition that does not improve or that deteriorates after administration of hydrocortisone, allergy to this compound should be considered.

MeSH terms

  • Administration, Topical
  • Anti-Inflammatory Agents / adverse effects*
  • Dermatitis, Contact / etiology*
  • Evaluation Studies as Topic
  • Humans
  • Hydrocortisone / adverse effects*
  • Hydrocortisone / analogs & derivatives*
  • Patch Tests / methods


  • Anti-Inflammatory Agents
  • tixocortol pivalate
  • Hydrocortisone