He-T family DNA sequences in the Y chromosome of Drosophila melanogaster share homology with the X-linked stellate genes

Chromosoma. 1991 Feb;100(2):118-24. doi: 10.1007/BF00418245.


The genome of Drosophila melanogaster contains a class of repetitive DNA sequences called the He-T family, which is unusual in being confined to telomeric and heterochromatic regions. The specific He-T fragment designated Dm665 was cloned in yeast by selection for an autonomously replicating sequence (ARS). Dm665 contains a restriction fragment length polymorphism (RFLP) that is specific to males and thus derives from the Y chromosome. Deletion mapping using X-Y translocations indicates that sequences homologous to Dm665 occur in at least one major cluster in each arm of the Y chromosome. Among 20 yeast artificial chromosome (YAC) clones containing Drosophila sequences homologous with Dm665, four clones derive from defined regions of the long arm of the Y and two from the short arm. The sequence of Dm665 is 2443 bp long, consists of 59% A + T, and contains no significant open reading frames or direct or inverted repeats. However, Dm665 contains a region of 650 bp that shares homology with portions of the X-linked locus Stellate.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Base Composition
  • Base Sequence
  • Chromosomes, Fungal
  • Cloning, Molecular
  • DNA*
  • Drosophila / genetics*
  • Female
  • Gene Library
  • Male
  • Molecular Sequence Data
  • Nucleic Acid Hybridization
  • Plasmids
  • Polymorphism, Restriction Fragment Length
  • Repetitive Sequences, Nucleic Acid*
  • Sequence Homology, Nucleic Acid*
  • X Chromosome*
  • Y Chromosome*


  • DNA

Associated data

  • GENBANK/D00847
  • GENBANK/S60911
  • GENBANK/S60914
  • GENBANK/S60917
  • GENBANK/S60919
  • GENBANK/S60920
  • GENBANK/S60969
  • GENBANK/S61524
  • GENBANK/S67999
  • GENBANK/X58155