Preparation and characterization of novel pyrrol-3-ones attached to alpha/beta-amino acids, esters and amides

Amino Acids. 2006 Nov;31(4):397-401. doi: 10.1007/s00726-006-0340-z. Epub 2006 May 26.


Various alpha/beta amino acid derivatives 5 were attached to compounds 3 to yield 2,3-dihydro-1H-pyrrol-3-ones amino acids derivatives 6. This rare heterocyclic amino acid skeleton including the pyrrolo[1,2-b][1,3]oxazol moiety was also successfully prepared in the esteric form. The structure of the new compounds was characterized by spectroscopic methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amides / chemistry*
  • Amino Acids / chemistry*
  • Esters / chemistry*
  • Molecular Structure
  • Pyrrolidinones / chemical synthesis*
  • Pyrrolidinones / chemistry


  • Amides
  • Amino Acids
  • Esters
  • Pyrrolidinones