Telomeric proteins: clearing the way for the replication fork

Nat Struct Mol Biol. 2006 May;13(5):386-7. doi: 10.1038/nsmb0506-386.

Abstract

Protein complexes at telomeres have been assumed to present an obstacle to the passing replication fork. The observation that the Schizosaccharomyces pombe telomere-binding protein Taz1 is required for replication suggests otherwise.

Publication types

  • News

MeSH terms

  • Animals
  • DNA Replication*
  • DNA, Fungal / biosynthesis
  • DNA, Fungal / genetics
  • DNA, Fungal / metabolism
  • Humans
  • Protein Binding
  • Schizosaccharomyces / genetics
  • Schizosaccharomyces / metabolism
  • Schizosaccharomyces pombe Proteins / genetics
  • Schizosaccharomyces pombe Proteins / metabolism*
  • Telomere / genetics
  • Telomere / metabolism*
  • Telomere-Binding Proteins / genetics
  • Telomere-Binding Proteins / metabolism*

Substances

  • DNA, Fungal
  • Schizosaccharomyces pombe Proteins
  • Telomere-Binding Proteins
  • taz1 protein, S pombe