Preventing depression among early adolescents in the primary care setting: a randomized controlled study of the Penn Resiliency Program

J Abnorm Child Psychol. 2006 Apr;34(2):203-219. doi: 10.1007/s10802-005-9014-7. Epub 2006 Apr 29.


This study evaluated the Penn Resiliency Program's effectiveness in preventing depression when delivered by therapists in a primary care setting. Two-hundred and seventy-one 11- and 12-year-olds, with elevated depressive symptoms, were randomized to PRP or usual care. Over the 2-year follow-up, PRP improved explanatory style for positive events. PRP's effects on depressive symptoms and explanatory style for negative events were moderated by sex, with girls benefiting more than boys. Stronger effects were seen in high-fidelity groups than low-fidelity groups. PRP did not significantly prevent depressive disorders but significantly prevented depression, anxiety, and adjustment disorders (when combined) among high-symptom participants. Findings are discussed in relation to previous PRP studies and research on the dissemination of psychological interventions.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analysis of Variance
  • California
  • Child
  • Cognitive Behavioral Therapy*
  • Depressive Disorder / prevention & control*
  • Depressive Disorder / psychology
  • Female
  • Health Maintenance Organizations
  • Humans
  • Male
  • Patient Compliance
  • Primary Health Care*
  • Sex Factors