Incidence of Guillain-Barré syndrome among patients with Campylobacter infection: a general practice research database study

J Infect Dis. 2006 Jul 1;194(1):95-7. doi: 10.1086/504294. Epub 2006 May 26.


The association between Campylobacter infection and subsequent Guillain-Barré syndrome (GBS) has been well documented. To date, however, there exists no direct estimate of the incidence of GBS among patients with Campylobacter infection. Using the General Practice Research Database, we estimate the incidence of GBS in a cohort of patients presenting with Campylobacter enteritis to be 1.17/1000 person-years, a rate 77 times greater than that in the general population. The probability that an individual who develops Campylobacter enteritis will also develop GBS during the subsequent 2-month period is <2/10,000.

MeSH terms

  • Adult
  • Aged
  • Campylobacter Infections / complications*
  • Campylobacter Infections / epidemiology
  • Campylobacter jejuni*
  • Cohort Studies
  • Databases, Factual
  • Enteritis / complications*
  • Enteritis / epidemiology
  • Enteritis / microbiology
  • Family Practice
  • Female
  • Guillain-Barre Syndrome / epidemiology*
  • Guillain-Barre Syndrome / etiology*
  • Humans
  • Incidence
  • Male
  • Middle Aged