Eosinophilic angiocentric fibrosis: an unusual entity producing complete lacrimal duct obstruction

Orbit. 2006 Jun;25(2):159-61. doi: 10.1080/01676830600674544.


Eosinophilic angiocentric fibrosis is an unusual fibrotic condition of unknown aetiology that tends to affect the upper respiratory tract. Twenty-one cases have been reported in the literature and only three have had ocular adnexal involvement. Despite characteristic histopathological and clinical findings, the diagnosis remains a challenge. Furthermore, its progressive nature with potential to invade adjacent structures and the lack of response to current treatment modalities make management difficult. We describe a case of sinonasal eosinophilic angiocentric fibrosis that presented with bilateral nasolacrimal duct obstruction.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Eosinophilia / pathology*
  • Fibrosis
  • Humans
  • Lacrimal Duct Obstruction / etiology*
  • Lacrimal Duct Obstruction / pathology
  • Male
  • Nose Diseases / pathology