Abstract
Commercial drugs, such as rimantadine, amantadine, rivabirine, and arbidole, are effective in suppressing the in vitro reproduction of highly pathogenic avian influenza A/H5N1 viruses. The study has used a porcine embryonic renal cell line and the highly pathogenic A/Duck/Novosibirsk/56/05 (H5N1) strain from a sick domestic duck (Anas platyrhynchos domesticus) (Chany Lake environs, Novosibirsk Region).
MeSH terms
-
Amantadine / pharmacology*
-
Animals
-
Animals, Domestic
-
Antiviral Agents / pharmacology*
-
Cell Line
-
Disease Outbreaks*
-
Dose-Response Relationship, Drug
-
Ducks
-
Indoles / pharmacology*
-
Influenza A Virus, H5N1 Subtype / drug effects*
-
Influenza A Virus, H5N1 Subtype / physiology
-
Influenza in Birds / epidemiology
-
Influenza in Birds / virology
-
Kidney
-
Microbial Sensitivity Tests
-
Poultry
-
Ribavirin / pharmacology*
-
Rimantadine / pharmacology*
-
Siberia / epidemiology
-
Swine
-
Virus Replication / drug effects
Substances
-
Antiviral Agents
-
Indoles
-
Rimantadine
-
Ribavirin
-
umifenovir
-
Amantadine