Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
, 75, 467-92

Dynamic Filaments of the Bacterial Cytoskeleton


Dynamic Filaments of the Bacterial Cytoskeleton

Katharine A Michie et al. Annu Rev Biochem.


Bacterial cells contain a variety of structural filamentous proteins necessary for the spatial regulation of cell shape, cell division, and chromosome segregation, analogous to the eukaryotic cytoskeletal proteins. The molecular mechanisms by which these proteins function are beginning to be revealed, and these proteins show numerous three-dimensional structural features and biochemical properties similar to those of eukaryotic actin and tubulin, revealing their evolutionary relationship. Recent technological advances have illuminated links between cell division and chromosome segregation, suggesting a higher complexity and organization of the bacterial cell than was previously thought.

Similar articles

  • The Bacterial Cytoskeleton
    YL Shih et al. Microbiol Mol Biol Rev 70 (3), 729-54. PMID 16959967. - Review
    In recent years it has been shown that bacteria contain a number of cytoskeletal structures. The bacterial cytoplasmic elements include homologs of the three major types …
  • Dynamics of Bacterial Cytoskeletal Elements
    PL Graumann. Cell Motil Cytoskeleton 66 (11), 909-14. PMID 19466751. - Review
    Bacterial cytoskeletal elements are involved in an astonishing spectrum of cellular functions, from cell shape determination to cell division, plasmid segregation, the po …
  • Molecules of the Bacterial Cytoskeleton
    J Löwe et al. Annu Rev Biophys Biomol Struct 33, 177-98. PMID 15139810. - Review
    The structural elucidation of clear but distant homologs of actin and tubulin in bacteria and GFP labeling of these proteins promises to reinvigorate the field of prokary …
  • Bacterial Ancestry of Actin and Tubulin
    F van den Ent et al. Curr Opin Microbiol 4 (6), 634-8. PMID 11731313. - Review
    The structural and functional resemblance between the bacterial cell-division protein FtsZ and eukaryotic tubulin was the first indication that the eukaryotic cytoskeleto …
  • Bacterial Filament Systems: Toward Understanding Their Emergent Behavior and Cellular Functions
    YJ Eun et al. J Biol Chem 290 (28), 17181-9. PMID 25957405. - Review
    Bacteria use homologs of eukaryotic cytoskeletal filaments to conduct many different tasks, controlling cell shape, division, and DNA segregation. These filaments, combin …
See all similar articles

Cited by 76 PubMed Central articles

See all "Cited by" articles

Publication types

MeSH terms

LinkOut - more resources