Partial prostatectomy using Nd:YAG laser for management of canine prostate carcinoma

Vet Surg. 2006 Jun;35(4):406-11. doi: 10.1111/j.1532-950X.2006.00165.x.


Objective: To report a technique for partial prostatectomy by laser dissection and to evaluate outcome and complications in dogs with prostate carcinoma (PCA).

Study design: Experimental and clinical case series.

Animals: Four normal dogs and 8 dogs with PCA.

Methods: Subcapsular partial prostatectomy, sparing the urethra and the dorsal aspect of the prostatic capsule, using Nd:YAG laser dissection to remove the prostatic parenchyma and control hemorrhage was performed in 4 normal dogs and subsequently in 8 dogs with histologically confirmed PCA. Additional treatment of PCA dogs included local application of interleukin-2 and systemic administration of meloxicam. Prostate size, complications, and survival time were recorded. Laser-associated thermal damage to surrounding tissue was evaluated by histology.

Results: In normal dogs, no damage to the dorsal prostatic capsule or urethra was detected. In PCA dogs, median survival was 103 days (range, 5-239 days). Three dogs died from complications within 16 days, whereas 5 (median survival, 183 days; range, 91-239 days) had improvement or resolution of clinical signs. Urinary incontinence did not occur.

Conclusion: Laser assisted subcapsular partial prostatectomy can be performed in dogs with PCA without development of postoperative incontinence.

Clinical relevance: Subcapsular partial prostatectomy is a potential palliative treatment for PCA in dogs and may lead to the resolution of clinical signs for several months.

Publication types

  • Evaluation Study

MeSH terms

  • Animals
  • Case-Control Studies
  • Combined Modality Therapy
  • Dog Diseases / mortality
  • Dog Diseases / pathology
  • Dog Diseases / surgery*
  • Dogs
  • Laser Therapy / methods
  • Laser Therapy / veterinary*
  • Male
  • Netherlands / epidemiology
  • Postoperative Complications / veterinary
  • Prostatectomy / methods
  • Prostatectomy / veterinary*
  • Prostatic Neoplasms / surgery
  • Prostatic Neoplasms / veterinary*
  • Survival Analysis
  • Treatment Outcome