Effect of dobutamine stress on basal septal tissue dynamics in hypertensive patients with basal septal hypertrophy

J Hum Hypertens. 2006 Aug;20(8):628-30. doi: 10.1038/sj.jhh.1002041. Epub 2006 Jun 8.

Abstract

Left ventricular outflow tract (LVOT) obstruction has been classically observed in hypertrophic cardiomyopathy in which the LVOT obstruction is associated with asymmetric septal hypertrophy producing a systolic pressure gradient across the LVOT. Basal septal hypertrophy (BSH) with hypertension may result in dynamic LVOT obstruction as well. It was suggested that regional hypertrophy may be related to enhanced ventricular dynamics.

Publication types

  • Clinical Trial

MeSH terms

  • Cardiotonic Agents / pharmacology*
  • Dobutamine / pharmacology*
  • Echocardiography, Doppler
  • Female
  • Heart Septum / drug effects*
  • Heart Septum / pathology*
  • Heart Septum / physiopathology
  • Humans
  • Hypertension / physiopathology*
  • Hypertrophy / pathology*
  • Male
  • Middle Aged

Substances

  • Cardiotonic Agents
  • Dobutamine