Cancer immunotherapy and preclinical studies: why we are not wasting our time with animal experiments

Hematol Oncol Clin North Am. 2006 Jun;20(3):567-84. doi: 10.1016/j.hoc.2006.03.001.


Experimental research on the immune response to transplanted tumors has led to pioneering discoveries that laid many of the foundations for the current field of immunology. Experimental research in oncology has proven that murine and human tumors have antigens that are truly cancer specific. This article discusses research investigating how can antigens on cancer cells be used to help eradicate cancer.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animal Experimentation
  • Animals
  • Drug Evaluation, Preclinical / methods*
  • Humans
  • Immunotherapy / methods*
  • Neoplasms / therapy*
  • Therapeutic Human Experimentation