Water immersion is associated with an increase in aquaporin-2 excretion in healthy volunteers

Biochim Biophys Acta. 2006 Aug;1758(8):1111-6. doi: 10.1016/j.bbamem.2006.03.029. Epub 2006 Apr 24.

Abstract

Here, we report the alterations in renal water handling in healthy volunteers during a 6 h thermoneutral water immersion at 34 to 36 degrees C. We found that water immersion is associated with a reversible increase in total urinary AQP2 excretion.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aquaporin 2 / physiology*
  • Aquaporin 2 / urine
  • Arginine Vasopressin / urine
  • Creatinine / urine
  • Diuresis / physiology*
  • Humans
  • Immersion*
  • Male
  • Osmolar Concentration
  • Water / physiology*

Substances

  • AQP2 protein, human
  • Aquaporin 2
  • Water
  • Arginine Vasopressin
  • Creatinine